ATTR-CM is a life-threatening, progressive, infiltrative, rare disease that can often be overlooked as a cause of heart failure. Transthyretin (TTR) proteins with unstable structures misfold and aggregate into amyloid fibrils, which deposit in the heart and other organs.1-3 It is critical to recognize the diagnostic clues so you can identify this disease.
ATTR-CM:
The Disease
Understand ATTR-CM and why it is critical to recognize in the early stages of disease